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Humans contain three peroxisomal acyl-CoA oxidases, ACOX1, ACOX2, and ACOX3
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Controversially, emerging evidence suggest that metformin has potential clinical applications in stem cell medicine, regenerative medicine and anti-aging (Jiang and Liu, 2020)
It would be great to undertake studies with the newer dual agonists and polyagonists also in rare obesity syndromes such as AS, Prader-Willi syndrome, and Bardet-Biedl syndrome (just to name a few) as the clinical need for effective obesity/hyperphagia therapies in these patients is especially high, says Scherer
Am J Respir Cell Mol Biol 49:654661
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