New England Journal of Medicine , 387(3), 205-217
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Weight Loss Programs for Men If you've noticed more belly fat despite staying active, less energy, strength that's harder to build, or mental sharpness that's slipped that's not just aging and it's not a willpower problem
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Realistic 2026 Results: What the Data Shows Metric Typical IF Outcome (1012 Weeks) Weight Loss 711 pounds (roughly 35% of body weight) Fat Loss Primarily visceral (belly) fat Blood Pressure Significant reductions in those with high baseline levels Muscle Retention High (if paired with resistance training) Reduced calorie intake due to fewer meals Improved insulin sensitivity Increased fat burning during fasting periods However, IF does not directly suppress appetite, which is why many people struggle with hunger during fasting hours
Bachem MG, Schneider E, Gross H et al