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Abbreviations ME: -mercaptoethanol BrdU: 5-bromo-2-deoxyuridine BSA: Bovine serum albumin DAB: 3,3-diaminobenzidine DMEM: Dulbeccos modified Eagles medium ECL: Enhanced chemiluminescence GSSSG: Glutathione trisulfide HGF: Hepatocyte growth factor HRP: Horseradish peroxidase HS: Horse serum mAb: Monoclonal antibody LASSS: Lipoic acid trisulfide SDS: Sodium dodecyl sulfate TTBS: Polyethylene sorbitan monolaurate (Tween20)-Tris-buffered saline Y: Tyrosine residue References Honda, S

In diabetic rat models, semaglutide has been shown to restore redox homeostasis, modulate androgen levels, attenuate testicular inflammation, and alleviate diabetes-induced testicular damage by regulating the ferroptosis pathway (68)

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