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Once available, cagrilintide may be particularly suitable for patients who experience significant GI side effects with GLP-1 medications, those seeking an alternative mechanism for appetite control, or as part of combination therapy for enhanced results

The Cu(II)/Cu(I) redox couple generates reactive oxygen species through the Fenton-like pathway: Cu(II) + O Cu(I) + O Cu(I) + HO Cu(II) + OH + OH Hydroxyl radicals (OH) are highly reactive and immediately oxidize susceptible amino acids

Nature Medicine (2024) 4

doi:10.1016/S0140-6736(23)01461-2

Start slowly and increase the dosage if necessary