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Furthermore, excess GSSG is postulated to result in alteration of a variety of cell functions, including enzyme function, protein synthesis, cell integrity, microtubular function, transport processes, and release mechanisms
The biological plausibility for supplementation rests on restoring something the body already produces and utilizes
This mechanistic insight led to the discovery of the GSH precursor N -acetylcysteine (NAC) as an effective antidote against APAP toxicity in mice and in patients [10, 11]
Glycyl-L-histidyl-L-lysine copper complex occurs naturally in human plasma
Ethical statement Research with human subjects were conducted in compliance to guidelines: Ethical Regulations for Research Involving Human Subjects and Supplementary Ethical Regulations for Research Involving Human Subjects
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