ulcerative colitis and tirzepatide Mirikizumab Administered at the Same Time as in Adult Participants With Moderately to Severely Active Obesity or Overweight: Phase 3b Study (COMMIT-UC) Ozempic and Ulcerative Colitis: GLP-1

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This number likely underrepresents actual complications given that many adverse events go unreported

Thats a hard one to accept, but the evidence itself supports it

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[7] [12] However, Phase 2 trials are not powered to detect rare cardiovascular outcomes, and longer-term Phase 3 data including dedicated cardiovascular outcome trials will be essential to fully characterise the cardiac safety profile of retatrutide