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Why are we hearing so much about GLP-1s lately
To verify the importance of pocket size for ligand recognition of ShHTLs, a double mutation T190F/C194F and a triple mutation L124F/T190F/C194F of ShHTL7 were generated to introduce large side-chain amino acids to reduce the pocket size by partially mimicking ShHTL3
Therefore, higher plasma TMAO in humans was suggested as a marker of kidney damage [79]
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In TRIUMPH-4, it affected 8.8% of the 9mg group and 20.9% of the 12mg group, compared to just 0.7% on placebo
Zhou, S., Han, L
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