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In addition to the different study populations and study design in these trials, one potential reason for this heterogeneity in cardiovascular benefit is the structural differences among the GLP-1RAs used in these trials
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The SURMOUNT trials reported mean weight loss exceeding 20% at the highest tirzepatide doses
[3] Healthcare providers may also exercise caution when prescribing these medications to individuals with kidney disease or a history of suicidal ideation or behavior
Some peptides take a few minutes to fully dissolve, and that is completely normal
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