Insulin resistance in chronic kidney disease: a systematic review
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When IGF-1 receptors become less sensitive or when IGF-1 is not produced in sufficient quantities the entire somatotropic feedback system is affected
In conclusion, there is a plausible biological rationale for the disease-modifying effect of metabolic disorders in ALS and FTLD based on the aforementioned hypotheses
4.1.3 Diabetes mellitus link to epilepsy Diabetes mellitus associated with epilepsy involves multiple molecular mechanisms