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Although this study did not specifically focus on CIPN, it does suggest that melatonin might improve quality of life in cancer patients undergoing chemotherapy

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Other components in this family, including BMPR2 (FDR q-value = 0.125) and SMAD7 (FDR q-value = 0.223), also showed evidence of modest down-regulation while SMAD1 showed evidence of modest up-regulation (FDR q-value = 0.101)

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