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This can be viewed as a form of homeostatic plasticity, where the CAS enhances its activity to maintain a relatively constant level of neural firing in response to diminished peripheral sensory input
Wegovy (semaglutide) injection, for subcutaneous use: prescribing information
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For instance, a 2002 review discussing the classification of cellulite based on skin consistency referred to an edematous type, characterized by sensations of leg heaviness and soreness features that overlap with those of lipedema and likely contributed to diagnostic ambiguity.31 In some contexts, lipedema was even referred to as an extreme form of cellulite.32 This misclassification was likely influenced by shared epidemiological and clinical features, including female predominance, involvement of the lower body, and changes in subcutaneous adipose tissue
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