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Lets see what existing studiesalbeit mostly in animalstell us
The release of vasoactive intestinal peptide (VIP) and acetylcholine (Ach) by submucosal neurons stimulates the enterocyte and Cl enters by co-transport with sodium and potassium through the basolateral Na + -K + -2Cl channel
Morning administration in older populations produces minimal GH elevation due to compounding factors: lower pituitary GH stores, higher basal somatostatin tone, and reduced receptor density
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