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BAT, distinguished by its high mitochondrial density and extensive vascularization, dissipates energy by nonshivering thermogenesis, whereas WAT primarily serves as an energy storage depot and secretes a variety of metabolic hormones and cytokines [210]
the remainder supports local intestinal and hepatic antioxidant defense
As it has been suggested that NOX2 is important for the initial oxidative burst following SE that contributes to seizures in trauma and chemically induced epilepsy models (Zilberter et al., 2022), the efficacy of NOX inhibition in chronic epilepsy and in a clinically relevant window following a seizure inciting event needs further evaluation
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10.1186/s13054-014-0460-x 148 OzkokE.YorulmazH.AtesG.AksuA.BalkisN.ahin.et al (2016)
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