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Munger, R

International Journal of Sport Nutrition and Exercise Metabolism , 28 , 178-187

For many women with PCOS, the underlying insulin resistance is a chronic condition

Therefore, you should avoid milk thistle if you're allergic to the Asteraceae or Compositae plant families (which, aside from milk thistle, include chrysanthemums, daisies, sunflowers, and marigolds)

And for skin lightening specifically by directly influencing melanin production, it can help achieve desired pigmentation changes with consistent IV sessions

Multiple Sclerosis Multiple sclerosis (MS) is a chronic, progressive neuroinflammatory disorder characterized by immune-mediated damage to myelinated fibers, leading to demyelination, axonal degeneration, and lesion formation [127]