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Highlights GLP-1 medicines reduce fat and liver mass more rapidly than skeletal muscle (SKM) Running performance is maintained or improved in mice on GLP-1 medicine GLP-1 medicine modifies the SKM proteome despite similar weight loss as calorie restriction Patients on GLP-1 medicine slightly reduce SKM mass but largely maintain strength Summary The large decrease in body weight with glucagon-like peptide-1 (GLP-1) medicines raises concern about a loss of lean body mass (LBM) and skeletal muscle
Repeated measures ANOVA test was used for discrimination of the differences among the means in the studied time points, and finally with Bonferroni post hoc test
Schedule Common research planning uses once-daily subcutaneous injection
The Significant Role of Carnitine and Fatty Acids during Pregnancy, Lactation and Perinatal Period
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Clinical trials in Prader-Willi syndrome: a review
