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Muscle preservation: Because AOD 9604 targets adipose tissue specifically and does not suppress systemic anabolic signaling, researchers have hypothesized that it may allow for fat loss with less collateral impact on lean mass, though this has not been formally tested in head-to-head trials

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In a Phase 2b obesity trial , AOD-9604 did not produce statistically significant weight loss versus placebo , and pharmaceutical development was discontinued around 2007 [3] [4]