In newer phase 3 trials, researchers used doses like 2 mg, 4 mg, 6 mg, 9 mg, and 12 mg, still taken once a week and increased slowly over time
In the SURMOUNT-1 clinical trial, individuals with overweight/obesity without diabetes taking tirzepatide (5 mg, 10 mg, and 15 mg once weekly) lost 16%, 21.4%, and 22.5% of body weight, respectively, after 72 weeks
Flexible therapy: Multiple doses available to meet individual patient needs and goals
Microbial fermentation of dietary protein: an important factor in diet-microbe-host interaction
PubMed 16.Currie CJ, Morgan CL, Poole CD, Sharplin P, Lammert M, McEwan P
At that point, transitioning to injectable tirzepatide would be the evidence-based next step