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With that, DPP-4 inhibitors have a lower risk than GLP-1R agonists in leading to hypoglycemia
It is hypothesized that semaglutide may enter through circumventricular organs, specialized brain regions such as the area postrema that lack a traditional blood-brain barrier, or via slow, low-capacity transport mechanisms (Athauda et al., 2026)
Diabetes 73 , 292305 (2024)
& Standley, D
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