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If you develop severe allergic reactions such as difficulty breathing, facial swelling, or widespread rash after a B12 injection, call 999 or go to A&E immediately, as these may indicate anaphylaxis, though this is extremely rare

Journal of the American Academy of Dermatology, 39 (4 Pt 1), 578589

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Histamine is primarily metabolized via methylation and Phase 2 liver detoxification, both of which are heavily dependent on adequate glutathione availability

Keeping a diary helps tailor meal timing and injection strategies

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