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2 Ferroptosis overview In 2003, Dolma and colleagues identified a novel compound, Erastin, through synthetic lethality screening designed to discover anticancer agents
That said, large randomized human trials for specific indications (like hair loss or systemic anti-aging) are still limited
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Cell Biosci 9:91 Malherbe P, Richards JG, Gaillard H, Thompson A, Diener C, Schuler A, Huber G (1999) cDNA cloning of a novel secreted isoform of the human receptor for advanced glycation end products and characterization of cells co-expressing cell-surface scavenger receptors and Swedish mutant amyloid precursor protein
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