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5 Treatment In general, the treatment of DPN is based on three fundamental pillars: 1
Unlike conventional occupancy-driven inhibitors, PROTACs facilitate the selective degradation of target proteins, thereby offering an opportunity to achieve sustained and isoform-specific knockdown
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doi: 10.1016/j.expneurol.2018.06.009 314 ShimataniK.NakashimaY.HattoriM.HamazakiY.MinatoN
Neuroprotective actions of dietary choline
To target E2 to -cells without the undesirable effects of general estrogen therapy, we created fusion peptides combining active or inactive glucagon-like peptide-1 (GLP-1) and E2 in a single molecule (aGLP1-E2 and iGLP1-E2 respectively)
