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A 2026 UK evidence review of the maternal brain remodelling shown by Hoekzema 2017 and Pritschet 2024, the Davies 2018 cognition meta-analysis, the postpartum estradiol-BDNF crash, allopregnanolone and zuranolone, sleep, thyroid and iron drivers and why pregnancy and breastfeeding are absolute contraindications Read the full review Neuroscience 1 June 2026 Dihexa for Endometriosis Brain Fog & Endo-Associated Cognitive Dysfunction: The 2026 UK Review Rigorous 2026 UK review of Dihexa for endometriosis brain fog and endometriosis-associated cognitive dysfunction
This may include: Assessment for fecal impaction (digital rectal exam or imaging) Evaluation for other causes of constipation (hypothyroidism, medication interactions, structural issues) Discussion of dose reduction or treatment alternatives Prescription motility agents (prucalopride, linaclotide) Referral to gastroenterology for refractory cases Foods and supplements that worsen GLP-1 constipation Constipating foods to limit or avoid: Processed foods low in fiber
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