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Additionally, treatment with GLP-1RAs was found to upregulate the expression of pulmonary surfactant proteins A and B, contributing to improved respiratory physiology (Wang et al., 2023b)
It also enhances the activity of detoxification enzymes, such as glutathione S-transferases (GSTs), which conjugate toxins to Glutathione, facilitating their elimination (Lu, 2013)
Generic protocols from the internet ignore most of that
Empagliflozin inhibits Na+/H+ exchanger activity in human atrial cardiomyocytes
Awad, A
And the program has to do with the coordination of many different genes, and these master regulator transcription factors are part of that process
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