Ovarian inflammation and POI Animal studies have demonstrated a significantly increase in pro-inflammatory cytokines (TNF-, IL-1, IL-6, and iNOS) in the ovaries of POI models, with anti-inflammatory and anti-oxidative stress treatments showing efficacy in improving ovarian function [82, 286, 287]
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TABLE 1 Demographics and clinical characteristics of sample population
demonstrated that STARD3 depletion substantially reduces the proportion of lysosomes that form contact sites with mitochondria (Hglinger et al., 2019)
[5] PubChem CID 950107 5-Amino-1-methylquinolinium (cation entry)
17: 156.Google Scholar Wilson, RD, Johnson, JA, Wyatt, P et al