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In the previous paper, we reported that protective mechanisms mediated by proline supplementation in GalN-induced liver injury is attributable to the early regenerative response thorough the activation of NF-B/IL-6/STAT3 pathway and early reduction of inflammation (Obayashi et al
Serine starvation induces stress and p53-dependent metabolic remodelling in cancer cells
Anticancer DNA vaccine based on human telomerase reverse transcriptase generates a strong and specific T cell immune response
These findings establish the mechanistic basis for the compound and provide proof of concept for its metabolic effects
PMID: 61 LernerABCaseJDHeinzelmanRV
Acknowledgments This work was supported in part by the Japan Study Group of NAFLD (JSG-NAFLD, Kyoto, Japan)
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