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In terms of injection site reactions, Tirzepatide had more (8.6% vs 0.3%), but no severe injection reactions were observed
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There is growing evidence that the microbiome may be critical for establishing, maintaining, and reversing obesity 14,15,16 , and that both diet composition and adiposity each contribute to modulation of the mouse gut microbiome profile 49
Nausea, diarrhea, constipation, and decreased appetite are most common
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