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Therefore, BMP4 plays a protective role against IR and T2DM [43]
10 Since adipogenesis can be considered an energy-consuming process, AMPK acts as a negative regulator of adipogenesis and can be considered a target for the treatment of obesity
doi:10.1186/s12970-018-0247-6 Sikiric P, Drmic D, Sever M, et al
10.1016/j.jcmgh.2017.06.001 Cell Mol Gastroenterol Hepatol
**Lower cost** AOD-9604 was historically cheaper than GLP-1 medications However, the clinical reality is that AOD-9604 failed its pivotal weight loss trial
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