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Nagasawa - University of Minnesota Twin Cities | UMN Center for Drug Design Ph.D

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Brand-name somatropin costs $800-$3,000+ per month at therapeutic doses through pharmacy channels, driven by complex manufacturing (recombinant protein production) and pharmaceutical distribution overhead

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We therefore turned back to our parsimonious model (equations 14 and Figs 1 and 2) and asked whether elimination of TAX6/Calcineurin from the circuit will recapitulate the experimental results

To overcome these limitations, the researchers designed and synthesized novel small molecules with improved metabolic stability, BBB penetrability, and oral activity