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Oxidants in cigarette smoke
Note: because the trials differed in design, population and duration, the values should not be interpreted as direct comparative efficacy
Oxidized roGFP2 WT , PfGrx C88S , and PfGrx C32S/C88S were produced by incubation of the reduced enzymes with 5 mM Diamide for 60 min on ice
These models may not fully recapitulate the chronic, multifactorial nature of human ocular diseases like DR, which involves decades of metabolic dysregulation and low-grade inflammation [130,131,132,133]
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