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The primary commercial focus is psychiatric and addiction indications where the adherence benefit of monthly dosing and the reward-circuit mechanism of GLP-1 agonism both matter
Findings are preliminary and have not been replicated in robust human trials
We need more than one drug in each class because there are differences in the medications
While Wegovy has shown promise for weight management in non-pregnant individuals, its effects on pregnancy and fetal development are not well understood
Baek SH, Ko J-H, Lee H, Jung J, Kong M, Lee J-w, Ahn KS (2016) Resveratrol inhibits STAT3 signaling pathway through the induction of SOCS-1: role in apoptosis induction and radiosensitization in head and neck tumor cells
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