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Acta Orthop Traumatol Turc
Because collagen acts as the structure that holds everything up, a lack of it causes skin to sag or wrinkle
Your diet is another major factor
Based on these findings, Eisai conducted a Phase 2/3 trial (NCT00444613) in Japan to evaluate the safety and efficacy of ultrahigh-dose methylcobalamin injections in 373 adults whose ALS symptoms began up to three years before enrollment
PMID: 41754849
Some trial participants showed total body weight reductions in the 20-25% range, though these figures come from smaller, shorter studies and should be interpreted with caution until phase 3 data is published
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