(This might relate to propofols inhibition of NMDA receptors, which blocks tolerance and withdrawal.) Propofol suppresses respiration, which can be helpful among ventilated patients to reduce ventilator dyssynchrony
Athletes subject to anti-doping rules should not use any of them
10.18632/oncotarget.20524 89 MiljkovicM.SeguinA.JiaX.CoxJ
JACC Basic to Trans science (2018) 3(6):84457
From the Australian public healthcare perspective, this came at an incremental cost of AU$4.2 billion for SGLT2is and AU$20.2 billion for GLP-1 RAs, with corresponding ICERs of AU$23,717 and AU$100,705 per QALY gained, respectively
But, even if it is the case that the risk of thyroid cancer turns out to be complete noise, it still wouldnt change the fact that most people would be better off avoiding GLP-1 agonists for the reasons listed here