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Insulin resistance especially fits this perfectly, it builds silently for years before a single lab result actually shows it, and by then the body has already been compensating for a long time

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Nagyova E, Nemcova L, Bujnakova Mlynarcikova A, Blaha M, Prochazka R, Scsukova S (2017) Effect of bone morphogenetic protein-15 on gonadotropin-stimulated synthesis of hyaluronan and progesterone in porcine ovarian follicle

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This 3-6 fold increase in oxalate absorption is significant, especially if paired with a genetic susceptibility or with a high oxalate diet.[ref] Enteric hyperoxaluria is a metabolic disorder that is primarily due to increased absorption of dietary oxalates