Although the retro-inverso approach may fail to accurately reproduce biological function in the context of helical structures (e.g., p53 or HIV-1 proteins), certain exceptionssuch as the binding of a p53-derived retro-inverso peptide to its regulator MDM2demonstrate that well-designed D-peptides can, in specific cases, effectively mimic the function of the original peptide
Obesity: Excess weight can exacerbate symptoms of BPH
Beck, A., Goetsch, L., Dumontet, C
Stimulating Th1 responses in a patient with rheumatoid arthritis, lupus, or multiple sclerosis could theoretically worsen disease, though this has not been systematically studied in those populations
Indirectly, yes
The implicated lettuce was recalled more than a week ago, and lettuce is perishable, so it cleared shelves quickly