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By contrast, PG-102 markedly preserved -cell area and islet architecture, consistent with its robust glycemic effects (Fig

Rather, GLP-1 therapies appear to support the biological environment in which these processes unfold

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So adjunctive therapies are supposed to be therapies that help insulin with glucose-lowering. The history of adjunctive therapies in type 1 diabetes began with metformin, an oral medication approved in the U.S