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While the observed associations do not establish causality, they highlight the importance of vigilance for potential NAEs during treatment, particularly given the heterogeneous temporal patterns of onset across events

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Once absorbed, GLP-1 medications circulate throughout your entire body

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Before treatment, skin may look dull or uneven

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However, these medications are costly, in high demand and produce variable results driving the need for more obesity treatment options

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Using lower doses of semaglutide is cheaper for patients, results in fewer side-effects and helps ensure that stocks of the drug, which are still limited, go further. Tapering semaglutide 353 of the 2,246 patients (83% female, median age 49 years, median BMI 31.5, average body weight 92kg/14st 7lb) started to taper off semaglutide after they had reached their target weight

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