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The medication is doing significant work
Labs precede GLP-1 protocol initiation
Canada has much stricter rules around prescription drug advertising
In the PIONEER 4 trial, patients on 14 mg lost an average of around 9 pounds over six months
Serious adverse effects requiring immediate medical attention include: Severe abdominal pain that may indicate pancreatitis (inflammation of the pancreas) Persistent nausea and vomiting leading to dehydration Changes in vision or eye pain (particularly in patients with type 2 diabetes and pre-existing retinopathy) Signs of thyroid tumors (neck mass, difficulty swallowing, persistent hoarseness) Symptoms of gallbladder disease (upper right abdominal pain, fever, jaundice) Severe allergic reactions (rash, difficulty breathing, swelling) These medications carry a boxed warning regarding thyroid C-cell tumors observed in rodent studies, though there is no definitive evidence of this risk in humans
Ozempic and Rybelsus also contain semaglutide, but they are more commonly associated with blood sugar treatment, though they may come up in weight-loss conversations as well
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