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Initially investigated for the management of diabetes, their marked weight-loss induction effects led to their increasing use off-label for weight loss

Jacob RA, Aiello GM, Stephensen CB, Blumberg JB, Milbury PE, Wallock LM et al

Given the established protective properties of both SGLT-2Is and GLP-1RAs on kidney function, this finding is unexpected if it truly represents the degree of fibrosis, suggesting that the observed changes in ADC may represent other changes in kidney microstructure

Has seen a dietitian and a personal trainer

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