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Amylin and Cagrilintide activate CGRP-like neurons in the AP that project to: Nucleus tractus solitarius (NTS) , autonomic center Parabrachial nucleus , integration of taste and satiety Hypothalamic pathways , energy balance The result: strong central appetite suppression and stabilization of satiety between meals

Sufyan et al., 2021

Res Chem Intermed 48(5):20472067

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It tested oral doses of 0.25, 0.5, or 1 mg per day against placebo

BPC-157 is derived from a protein in gastric juice., meaning, it is NOT a natural substance that exists in nature