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Beyond inducing the secretion of classical inflammatory mediators such as IL-6 and CXCL8 (72), IL-17A activates IKK to promote the epithelial release of thymic stromal lymphopoietin (TSLP), amplifying local type 2 inflammation and fibrotic signals (81)

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We recognize that accurate dosing is crucial, as improper administration can lead to ineffective treatment or even adverse effects

Benefits and harms of once-weekly glucagon-like peptide-1 receptor agonist treatments a systematic review and network meta-analysis comparative clinical profiles of once-weekly GLP-1RAs

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The incretin effectthe phenomenon whereby oral glucose intake produces a greater insulin response than intravenous glucose administrationis largely mediated by GIP and GLP-1