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My message to patients is that we can do an excellent job of managing the condition compared to 20 years ago, says Roberto Caricchio, MD, the division chief of rheumatology at UMass Memorial Medical Center in Worcester, Massachusetts

That said, more recent human trial data have begun to provide greater clarity regarding the translational potential of GLP-1 therapies in Alzheimers disease, helping to refine which aspects of these theoretical benefits may ultimately prove clinically meaningful

The effect was very strong, nearly 30% reduction with metformin alone (first line treatment for type 2 diabetes) but an additional 40% with GLP-1 receptor agonists (eg, Wegovy [semaglutide, Novo Nordisk]), and unexpectedly it was effective for all asthma patients, including those with higher or lower BMI, and with all different types of asthma, Chloe I

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Some patients seek its alternatives due to affordability issues, side effects, insufficient results, and the shortage of the medication