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Nature 429, 184187
It compared people taking semaglutide at the 2.4mg dose (Wegovy) in combination with lifestyle changes (diet and exercise programs) with people who only made lifestyle changes
Participants who continued with tirzepatide lost an additional 5% of their body mass over the next 52 weeks, underscoring its lasting effectiveness
This applies to both Zepbound and Mounjaro, whether in prefilled pens or single-dose vials
they simplify logistics, reduce cold-chain dependencies, and enable more flexible dosing, ultimately enhancing accessibility and compliance
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