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People in one study lost an average of about 6% of their body weight over six months while taking metformin

The most common side effects (incidence 5%) include nausea, diarrhea, vomiting, constipation, stomach-area pain, heartburn, injection-site reactions, sleepiness, allergic reactions, burping, hair loss and acid reflux disease

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In fact, some analyses suggest lower recurrence rates or improved outcomes in those who develop pancreatitis while on therapy