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Refrigeration temperature must stay between 28C continuously
Across GLP-1 trials, about 60% of lost weight returns within a year and about 75% over the longer regain curve. Continued treatment has stronger evidence than complete withdrawal
The arrival of oral semaglutide as a weight loss treatment marks a genuine turning point in obesity medicine
Those drugs have different molecular structures than orforglipron, Wharton says, which could explain why orforglipron didnt cause the same trouble
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