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This allows the peptides to penetrate deeply, speeding up the healing of acne lesions, reducing inflammation, and preventing future breakouts

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The proposed mechanism involves potentiation of existing opioid tone rather than direct opioid receptor agonism, which may explain the absence of classical tolerance and dependence patterns

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Archived from the original on 11 February 1998

What is happening physiologically: Two weeks of consistent DSIP dosing has established ongoing modulation of the HPA axis and circadian regulatory systems