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2 In 2024, the approved commercial versions of semaglutide are Ozempic 3-4 , Rybelsus 3,5 , and Wegovy injection 3,6 , developed by Novo Nordisk
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By activating the GLP-1 receptor, GLP-1RA enhances insulin secretion and inhibits glucagon secretion to lower blood glucose, ingeniously suppressing appetite, increasing satiety, and delaying gastric emptying, thus achieving weight reduction (Torekov et al., 2011
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Some of these studies find that semaglutide is unlikely to be cost-effective [54, 55], while others reported support for the likely cost-effectiveness of semaglutide [56]
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