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The molecule was designed so that all three receptor activities are present at meaningful but balanced potencies: too much glucagon-receptor activation would raise hepatic glucose output and undo the glycaemic benefit, whereas too little would lose the energy-expenditure arm that motivates including glucagon in the first place
doi: 10.1016/s0928-4257(99)00119-9
I used to have to take a nap after school, says Frankie, now 17
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