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Current limitations include: limited long-term safety data compared with established medicines trial populations that may not represent broader real-world groups evolving phase 3 research ongoing monitoring of adverse events the need for longer follow-up across different study populations This does not make the available data unimportant

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Rodbard HW, Rosenstock J, Canani LH, Deerochanawong C, Gumprecht J, Lindberg S, et al