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however, this is FDA staff's proposed position going into the meeting, not a final action, and the committee's discussion, any vote, and FDA's ultimate decision are still pending, so the outcome of the review is not yet known

Cellular Senescence Research: the compound is studied in longevity and cellular senescence models where NAD+ decline is a characterized feature

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Oral corticosteroids (prednisone) provide short-term anti-inflammatory benefit but have significant side effect profiles with repeated courses, including bone density loss, immune suppression, and metabolic disruption