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Given the drugs impact on reducing appetites and calorie intake, increasing AOM prevalence can shape demand for food, beverages and restaurants, and we anticipate meaningful impact in areas such as packaged food and beverages, restaurants, grocery stores and weight loss programs. While its early days, AOM patients report a 23% reduction in daily meals and 50% reduction in snacks, according to Morgan Stanley
Logistic issues: Extremely expensive (e.g., ~$25,000/treatment)
Excess fat storage in the liver worsens metabolic dysfunction, creating a vicious cycle
Individual variation in side effect onset stems from factors like body weight, metabolism, food intake, and genetic sensitivity to GLP-1 receptor signaling
SGLT2 inhibitors in combination therapies for tumors: a novel approach to synergistic treatment strategies
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